Division of Radiology - (Research Activities)

Laboratory of Medical Imaging

(A. Karantanas, D. Tsetis, A. Hatzidakis, M. Raissaki, E. Papadaki)
Inflammatory and neoplastic diseases of the small bowel.
Bone marrow disorders.
Imaging and image guided treatment of sports injuries.
Imaging of rheumatological disorders.
Spinal imaging and intervention.
Imaging and interventional procedures of pancreatic and biliary disorders.
Diagnosis and percutaneous treatment of vascular disorders.
MRI of abdominal disorders.
Newer MRI techniques in imaging of CNS infection demyelination, neoplasms and epilepsy. Contrast media applications in ultrasonography.
MR urography applications in children.
Radiation protection in pediatric CT examinations.
CT perfusion applications.


Laboratory of Medical Physics

(J. Damilakis, K. Perisinakis, T. Maris, M. Mazonakis)
- Website: http://medicalphysics.med.uoc.gr/
Development of methods for the estimation of radiation dose and risk
- to conceptus from radiological exposures performed on the expectant mother
- to patients undergoing radiological procedures
- to occupationally exposed medical stuff
Exposure parameter optimization in radiography, fluoroscopy and CT imaging.
Monte Carlo simulation of photon beams from linear accelerators for the radiation dose calculation and the evaluation of dose distributions in pregnant and/or pediatric patients undergoing radiotherapy treatment.
Gel dosimetry techniques for radiotherapy treatment planning verification.
Development of MR maging protocols for the quantitative assessment of osteoporosis and hemosiderosis in multi-transfused thalassemic patients.
Design and development of quality control procedures and software tools for Magnetic Resonance Imaging systems.
Development and evaluation of computerized methods for organ volume measurements on CT and/or MR images.
Leakage determination of chemotherapeutic agents during isolated limb perfusion using the radioisotopic method.
Optimization of bone densitometry methods (DXA, QCT, QUS, MR)


Laboratory of Nuclear Medicine

(S. Koukouraki)
Evaluation of response to chemoradiotherapy. Labelling of several chemotherapeutics in collaboration with the research center «DEMOKRITOS». Scintimammography and lymphatic mapping using the radioisotopic probe. Myocardial perfusion SPECT in patients with CAD. Radiolabeled WBCs in Inflammatory bowel disease. 123I MIBG scintigraphy: cardiac adrenergic imaging in Heart Failure. Diabetes Mellitus and Hyperlipidemia. Scintigraphic evaluation of rennin-angiotensin dependent hypertension. Qualitative and quantitative evaluation of brain SPECT in patients with Parkinson’s disease. Differential diagnosis Parkinson’s disease vs Parkinson plus syndromes using combined radioisotopique techniques. Application of brain perfusion SPECT using HMPAO in patients with NPSLE. Combined Diffusion- Perfusion MR and SPECT HMPAO in patients with neuropsychiatric lupus erythematous. Radioisotopique techniques for the evaluation of gastric and intestinal motility after sleeve gastrectomy. Brain tumors. Evaluation of grading between low and high grade glioblastomas compared to the histopathological data. Screening for hepatopulmonary syndrome in cirrhotic patients. Correlation with clinical data. Combined 99mTc-besilesomab and bone marrow imaging in diagnosis of prosthetic joint infection.


Laboratory of Radiotherapy and Radiation Oncology

(H. Varveris)

The academic - research interests of the Department (5 Specialized Physicians, 2 Trainee Doctors) are focused on:
A) The use of Concurrent Chemoradiation for any kind of tumors treated radically and/or with an Adjuvant intent (External Beam Radiotherapy - Brachytherapy after Surgery and/or Chemotherapy)
- Carcinoma of the G.I. Tract (Esophagus, Stomach, Pancreas, Hepatobiliary, Colon, Rectum)
- Head and Neck Tumors
- Gliomas and other CNS tumors
- Thoracic Neoplasms (Lung Cancer, Tumors of the Mediastinum)
- Genitourinary Tumors (Testis, Prostate, Penus, Bladder, Kidney)
- Gynecological Neoplasms (Cervical, Endometrial, Vulvar, Vaginal and Ovarian Carcinomas)
- Breast tumors
- Soft tissue Sarcomas
- Childhood Cancers
- Lymphomas and Haematologic Malignancies
B) In addition, research has been made regarding the concomitant use of Irradiation to Monoclonal Antibodies (moAb) raised against EGFR - Receptor for Head & Neck / Breast / Lung / and Uterine Cervix Carcinoma Patients
C) In collaboration with the Clinical Oncology Department, Phase I/II trials have been conducted concerning Radiation treatment of Gliomas and Colorectal Carcinomas concurrently or sequentially with Bevacizumab (a VEGF - R moAb).
D) The experimental use of Immunotherapy for patients with Lung Cancer, Melanoma and Grawitz tumors of the Kidney.
E) Moreover, in combination with the Medical Physics Department, Studies have been made regarding Radiation doses to conceptus following different Radiotherapy schedules and/or Radiodiagnostic procedures, to estimate the corresponding Radiogenic risk.
F) Furthermore, with the Physicists, the RT Therapists, Nurses, and the Administrator employee, a Quality Assurance Committee has been formed to monitor the quality and appropriateness of patient care, regarding Equipment and Treatment Outcomes as well as the Frequency and Seriousness of treatment induced sequelae.