Basic Sciences - (Recent Publications 2018)
2018
| Tsoka P, Matsumoto H, Maidana DE, Kataoka K, Naoumidi I, Gravanis A, Vavvas DG, Tsilimbaris MK. Effects of BNN27, a novel C17-spiroepoxy steroid derivative, on experimental retinal detachment-induced photoreceptor cell death. Sci Rep. 2018 Jul 13;8(1):10661. doi: 10.1038/s41598-018-28633-1. PubMed PMID: 30006508; PubMed Central PMCID: PMC6045604. |
| Karageorgos V, Venihaki M, Sakellaris S, Pardalos M, Kontakis G, Matsoukas MT, Gravanis A, Margioris A, Liapakis G. Current understanding of the structure and function of family B GPCRs to design novel drugs. Hormones (Athens). 2018 Mar;17(1):45-59. doi: 10.1007/s42000-018-0009-5. Epub 2018 Apr 19. Review. PubMed PMID: 29858864. |
| Liapakis G. Editorial: Corticotropin Releasing Factor (CRF) and Its Receptors: From Structure to Function in Health and Disease (Part II). Curr Mol Pharmacol. 2018;11(1):2-3. doi: 10.2174/187446721101180103122730. PubMed PMID: 29370747. |
| Durdagi S, Aksoydan B, Erol I, Kantarcioglu I, Ergun Y, Bulut G, Acar M, Avsar T, Liapakis G, Karageorgos V, Salmas RE, Sergi B, Alkhatib S, Turan G, Yigit BN, Cantasir K, Kurt B, Kilic T. Integration of multi-scale molecular modeling approaches with experiments for the in silico guided design and discovery of novel hERG-Neutral antihypertensive oxazalone and imidazolone derivatives and analysis of their potential restrictive effects on cell proliferation. Eur J Med Chem. 2018 Feb 10;145:273-290. doi: 10.1016/j.ejmech.2017.12.021. Epub 2017 Dec 11. PubMed PMID: 29329002. |
| Rassouli O, Liapakis G, Venihaki M. Role of Central and Peripheral CRH in Skin. Curr Mol Pharmacol. 2018;11(1):72-80. doi: 10.2174/1874467209666161026144219. Review. PubMed PMID: 277842170. |
| Dermitzaki E, Venihaki M, Tsatsanis C, Gravanis A, Avgoustinaki PD, Liapakis G, Margioris AN. The Multi-faceted Profile of Corticotropin-releasing Factor (CRF) Family of Neuropeptides and of their Receptors on the Paracrine/Local Regulation of the Inflammatory Response. Curr Mol Pharmacol. 2018;11(1):39-50. doi: 10.2174/1874467210666170109164430. Review. PubMed PMID: 28103784. |
| Savaki H. A specific immunity brain aging gene with a future. EBioMedicine. 2018 Oct;36:9. doi: 10.1016/j.ebiom.2018.08.044. Epub 2018 Sep 27. PubMed PMID: 30268835; PubMed Central PMCID: PMC6197387. |
| Sapountzis P, Paneri S, Gregoriou GG. Distinct roles of prefrontal and parietal areas in the encoding of attentional priority. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8755-E8764. doi: 10.1073/pnas.1804643115. Epub 2018 Aug 28. PubMed PMID: 30154164; PubMed Central PMCID: PMC6140495. |
| Agapaki OM, Christakos CN, Anastasopoulos D. Characteristics of Rest and Postural Tremors in Parkinson's Disease: An Analysis of Motor Unit Firing Synchrony and Patterns. Front Hum Neurosci. 2018 May 1;12:179. doi: 10.3389/fnhum.2018.00179. eCollection 2018. PubMed PMID: 29780311; PubMed Central PMCID: PMC5946021. |
| Neromyliotis E, Moschovakis AK. Response properties of saccade-related neurons of the post-arcuate premotor cortex. J Neurophysiol. 2018 Jun 1;119(6):2291-2306. doi: 10.1152/jn.00669.2017. Epub 2018 Mar 14. PubMed PMID: 29537912. |
| Sapountzis P, Gregoriou GG. Neural signatures of attention: insights from decoding population activity patterns. Front Biosci (Landmark Ed). 2018 Jan 1;23:221-246. Review. PubMed PMID: 28930544. |
| Kalemaki K, Konstantoudaki X, Tivodar S, Sidiropoulou K, Karagogeos D. Mice With Decreased Number of Interneurons Exhibit Aberrant Spontaneous and Oscillatory Activity in the Cortex. Front Neural Circuits. 2018 Oct 31;12:96. doi: 10.3389/fncir.2018.00096. eCollection 2018. PubMed PMID: 30429776; PubMed Central PMCID: PMC6220423. |
| Rieckher M, Markaki M, Princz A, Schumacher B, Tavernarakis N. Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans. Cell Rep. 2018 Oct 2;25(1):199-211.e6. doi: 10.1016/j.celrep.2018.09.009. PubMed PMID: 30282029; PubMed Central PMCID: PMC6180348. |
| Daskalaki I, Gkikas I, Tavernarakis N. Hypoxia and Selective Autophagy in Cancer Development and Therapy. Front Cell Dev Biol. 2018 Sep 10;6:104. doi: 10.3389/fcell.2018.00104. eCollection 2018. Review. PubMed PMID: 30250843; PubMed Central PMCID: PMC6139351. |
| Palikaras K, Lionaki E, Tavernarakis N. Mechanisms of mitophagy in cellular homeostasis, physiology and pathology. Nat Cell Biol. 2018 Sep;20(9):1013-1022. doi: 10.1038/s41556-018-0176-2. Epub 2018 Aug 28. Review. PubMed PMID: 30154567. |
| Kourtis N, Tavernarakis N. Small heat shock proteins and neurodegeneration: recent developments. Biomol Concepts. 2018 Aug 20;9(1):94-102. doi: 10.1515/bmc-2018-0009. Review. PubMed PMID: 30133417. |
| Markaki M, Palikaras K, Tavernarakis N. Novel Insights Into the Anti-aging Role of Mitophagy. Int Rev Cell Mol Biol. 2018;340:169-208. doi: 10.1016/bs.ircmb.2018.05.005. Epub 2018 Jun 20. Review. PubMed PMID: 30072091. |
| Gkikas I, Palikaras K, Tavernarakis N. The Role of Mitophagy in Innate Immunity. Front Immunol. 2018 Jun 5;9:1283. doi: 10.3389/fimmu.2018.01283. eCollection 2018. Review. PubMed PMID: 29951054; PubMed Central PMCID: PMC6008576. |
| Witter MP, Karagogeos D, Van Bockstaele EJ, Segal RA. A transatlantic cooperation for enriched neuroscience training. Eur J Neurosci. 2018 Jul;48(2):1717-1719. doi: 10.1111/ejn.14056. Epub 2018 Jul 4. PubMed PMID: 29938860. |
| Metaxakis A, Petratou D, Tavernarakis N. Multimodal sensory processing in Caenorhabditis elegans. Open Biol. 2018 Jun;8(6). pii: 180049. doi: 10.1098/rsob.180049. Review. PubMed PMID: 29925633; PubMed Central PMCID: PMC6030117. |
| Metaxakis A, Ploumi C, Tavernarakis N. Autophagy in Age-Associated Neurodegeneration. Cells. 2018 May 5;7(5). pii: E37. doi: 10.3390/cells7050037. Review. PubMed PMID: 29734735; PubMed Central PMCID: PMC5981261. |
| Nikoletopoulou V, Tavernarakis N. Regulation and Roles of Autophagy at Synapses. Trends Cell Biol. 2018 Aug;28(8):646-661. doi: 10.1016/j.tcb.2018.03.006. Epub 2018 May 3. Review. PubMed PMID: 29731196. |
| Hotzi B, Kosztelnik M, Hargitai B, Takács-Vellai K, Barna J, Bördén K, Málnási-Csizmadia A, Lippai M, Ortutay C, Bacquet C, Pasparaki A, Arányi T, Tavernarakis N, Vellai T. Sex-specific regulation of aging in Caenorhabditis elegans. Aging Cell. 2018 Jun;17(3):e12724. doi: 10.1111/acel.12724. Epub 2018 Mar 1. PubMed PMID: 29493066; PubMed Central PMCID: PMC5946081. |
| Pietrocola F, Castoldi F, Markaki M, Lachkar S, Chen G, Enot DP, Durand S, Bossut N, Tong M, Malik SA, Loos F, Dupont N, Mariño G, Abdelkader N, Madeo F, Maiuri MC, Kroemer R, Codogno P, Sadoshima J, Tavernarakis N, Kroemer G. Aspirin Recapitulates Features of Caloric Restriction. Cell Rep. 2018 Feb 27;22(9):2395-2407. doi: 10.1016/j.celrep.2018.02.024. PubMed PMID: 29490275; PubMed Central PMCID: PMC5848858. |
| Princz A, Kounakis K, Tavernarakis N. Mitochondrial contributions to neuronal development and function. Biol Chem. 2018 Jun 27;399(7):723-739. doi: 10.1515/hsz-2017-0333. Review. PubMed PMID: 29476663. |
| Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review. PubMed PMID: 29362479; PubMed Central PMCID: PMC5864239. |
| Rieckher M, Psycharakis Daniele Ancora SE, Liapis E, Zacharopoulos A, Ripoll J, Tavernarakis N, Zacharakis G. Demonstrating Improved Multiple Transport-Mean-Free-Path Imaging Capabilities of Light Sheet Microscopy in the Quantification of Fluorescence Dynamics. Biotechnol J. 2018 Jan;13(1). doi: 10.1002/biot.201700419. Epub 2017 Dec 11. PubMed PMID: 29168308. |
| Konstantoudaki X, Chalkiadaki K, Vasileiou E, Kalemaki K, Karagogeos D, Sidiropoulou K. Prefrontal cortical-specific differences in behavior and synaptic plasticity between adolescent and adult mice. J Neurophysiol. 2018 Mar 1;119(3):822-833. doi: 10.1152/jn.00189.2017. Epub 2017 Nov 22. PubMed PMID: 29167323. |
| Zoupi L, Savvaki M, Kalemaki K, Kalafatakis I, Sidiropoulou K, Karagogeos D. The function of contactin-2/TAG-1 in oligodendrocytes in health and demyelinating pathology. Glia. 2018 Mar;66(3):576-591. doi: 10.1002/glia.23266. Epub 2017 Nov 22. PubMed PMID: 29165835. |
| Charmpilas N, Kounakis K, Tavernarakis N. Monitoring Mitophagy During Aging in Caenorhabditis elegans. Methods Mol Biol. 2018;1759:151-160. doi: 10.1007/7651_2017_18. PubMed PMID: 28324491. |
| Lang F, Leibrock C, Pandyra AA, Stournaras C, Wagner CA, Föller M. Phosphate Homeostasis, Inflammation and the Regulation of FGF-23. Kidney Blood Press Res. 2018;43(6):1742-1748. doi: 10.1159/000495393. Epub 2018 Nov 30. Review. PubMed PMID: 30504710. |
| Sukkar B, Hauser S, Pelzl L, Hosseinzadeh Z, Sahu I, Al-Maghout T, Bhuyan AAM, Zacharopoulou N, Stournaras C, Schöls L, Lang F. Inhibition of Lithium Sensitive Orai1/ STIM1 Expression and Store Operated Ca2+ Entry in Chorea-Acanthocytosis Neurons by NF-κB Inhibitor Wogonin. Cell PhysiolBiochem. 2018;51(1):278-289. doi: 10.1159/000495229. Epub 2018 Nov 19. PubMed PMID: 30453283. |
| Jaeger A, Zollinger L, Saely CH, Muendlein A, Evangelakos I, Nasias D, Charizopoulou N, Schofield JD, Othman A, Soran H, Kardassis D, Drexel H, Eckardstein AV. Circulating microRNAs -192 and -194 are associated with the presence and incidence of diabetes mellitus. Sci Rep. 2018 Sep 24;8(1):14274. doi: 10.1038/s41598-018-32274-9. PubMed PMID: 30250222; PubMed Central PMCID: PMC6155281. |
| Kallergi G, Aggouraki D, Zacharopoulou N, Stournaras C, Georgoulias V, Martin SS. Evaluation of α-tubulin, detyrosinated α-tubulin, and vimentin in CTCs: identification of the interaction between CTCs and blood cells through cytoskeletal elements. Breast Cancer Res. 2018 Jul 5;20(1):67. doi: 10.1186/s13058-018-0993-z. PubMed PMID: 29976237; PubMed Central PMCID: PMC6034292. |
| Theofilatos D, Fotakis P, Valanti E, Sanoudou D, Zannis V, Kardassis D. HDL-apoA-I induces the expression of angiopoietin like 4 (ANGPTL4) in endothelial cells via a PI3K/AKT/FOXO1 signaling pathway. Metabolism. 2018 Oct;87:36-47. doi: 10.1016/j.metabol.2018.06.002. Epub 2018 Jun 18. PubMed PMID: 29928895. |
| Goulielmaki E, Bermudez-Brito M, Andreou M, Tzenaki N, Tzardi M, de Bree E, Tsentelierou E, Makrigiannakis A, Papakonstanti EA. Pharmacological inactivation of the PI3K p110δ prevents breast tumour progression by targeting cancer cells and macrophages. Cell Death Dis. 2018 Jun 7;9(6):678. doi: 10.1038/s41419-018-0717-4. PubMed PMID: 29880805; PubMed Central PMCID: PMC5992183. |
| Lang F, Pelzl L, Hauser S, Hermann A, Stournaras C, Schöls L. To die or not to die SGK1-sensitive ORAI/STIM in cell survival. Cell Calcium. 2018 Sep;74:29-34. doi: 10.1016/j.ceca.2018.05.001. Epub 2018 May 3. Review. PubMed PMID: 29807219. |
| Zacharopoulou N, Tsapara A, Kallergi G, Schmid E, Alkahtani S, Alarifi S, Tsichlis PN, Kampranis SC, Stournaras C. The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells. Cell PhysiolBiochem. 2018;47(1):368-377. doi: 10.1159/000489917. Epub 2018 May 14. PubMed PMID: 29772566. |
| Livitsanou M, Vasilaki E, Stournaras C, Kardassis D. Modulation of TGFβ/Smad signaling by the small GTPaseRhoB. Cell Signal. 2018 Aug;48:54-63. doi: 10.1016/j.cellsig.2018.04.007. Epub 2018 Apr 26. PubMed PMID: 29705334. |
| Nomikou E, Livitsanou M, Stournaras C, Kardassis D. Transcriptional and post-transcriptional regulation of the genes encoding the small GTPasesRhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases. Cell Mol Life Sci. 2018 Jun;75(12):2111-2124. doi: 10.1007/s00018-018-2787-y. Epub 2018 Mar 2. Review. PubMed PMID: 29500478. |
| Zacharopoulou N, Tsapara A, Kallergi G, Schmid E, Tsichlis PN, Kampranis SC, Stournaras C. The epigenetic factor KDM2B regulates cell adhesion, small rho GTPases, actin cytoskeleton and migration in prostate cancer cells. Biochim BiophysActaMol Cell Res. 2018 Apr;1865(4):587-597. doi: 10.1016/j.bbamcr.2018.01.009. Epub 2018 Feb 2. PubMed PMID: 29408056. |
| Kallergi G, Vetsika EK, Aggouraki D, Lagoudaki E, Koutsopoulos A, Koinis F, Katsarlinos P, Trypaki M, Messaritakis I, Stournaras C, Georgoulias V, Kotsakis A. Evaluation of PD-L1/PD-1 on circulating tumor cells in patients with advanced non-small cell lung cancer. TherAdv Med Oncol. 2018 Jan 15;10:1758834017750121. doi: 10.1177/1758834017750121. eCollection 2018. PubMed PMID: 29383038; PubMed Central PMCID: PMC5784570. |
